Reading and Misreading 8-oxoguanine, a Paradigmatic Ambiguous Nucleobase
نویسندگان
چکیده
منابع مشابه
Robust Reading of Ambiguous Writing
A given entity, representing a person, a location or an organization, may be mentioned in text in multiple, ambiguous ways. Understanding natural language requires identifying whether different mentions of a name, within and across documents, represent the same entity. We develop an unsupervised learning approach that is shown to resolve accurately several aspects of the name identity and traci...
متن کاملpassivity in waiting for godot and endgame: a psychoanalytic reading
this study intends to investigate samuel beckett’s waiting for godot and endgame under the lacanian psychoanalysis. it begins by explaining the most important concepts of lacanian psychoanalysis. the beckettian characters are studied regarding their state of unconscious, and not the state of consciousness as is common in most beckett studies. according to lacan, language plays the sole role in ...
Thermodynamic and kinetic basis for recognition and repair of 8-oxoguanine in DNA by human 8-oxoguanine-DNA glycosylase
We have used a stepwise increase in ligand complexity approach to estimate the relative contributions of the nucleotide units of DNA containing 7,8-dihydro-8-oxoguanine (oxoG) to its total affinity for human 8-oxoguanine DNA glycosylase (OGG1) and construct thermodynamic models of the enzyme interaction with cognate and non-cognate DNA. Non-specific OGG1 interactions with 10-13 nt pairs within ...
متن کاملThe hunt for 8-oxoguanine deaminase.
An enzyme from Pseudomonas aeruginosa, Pa0142 (gi|9945972), that is able to catalyze the deamination of 8-oxoguanine (8-oxoG) to uric acid has been identified for the first time. 8-Oxoguanine is formed by the oxidation of guanine residues within DNA by reactive oxygen species, and this lesion results in G:C to T:A transversions. The value of k(cat)/K(m) for the deamination of 8-oxoG by Pa0142 a...
متن کاملEleanor Maccoby : How Much Do Parents Matter ? Reading and Misreading Behavior Genetics
Children Are Good Observers Children learn from actively investigating the world around them. Coming upon a construction site, for instance, a fouryear-old will be curious about the activity. The adult with the child should take the time to stop, really look at what’s going on, and direct the child’s attention to the details. “Let’s watch and see what happens while that dump truck unloads dirt....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Crystals
سال: 2019
ISSN: 2073-4352
DOI: 10.3390/cryst9050269